Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?
Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?
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DOI：
10.1038/s41415-020-1747-8
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发表时间：
2020-06-01
影响因子：
2.6
通讯作者：
Sampson, Ariane
中科院分区：
文献类型：
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作者：
Sampson, Victoria;Kamona, Nawar;Sampson, Ariane
于二零二零年一月三十日，世界卫生组织将由SARS-CoV-2病毒引起的COVID-19确定为全球紧急情况。已经确定的COVID-19感染并发症的风险因素包括年龄、性别和合并症，如糖尿病、高血压、肥胖和心血管疾病。然而，这些风险因素并不能解释另外52%的由COVID-19引起的通常看似健康的个体死亡。本文研究了SARS-CoV-2和细菌负荷之间的潜在联系，质疑细菌是否可能在细菌重叠感染和并发症（如肺炎，急性呼吸窘迫综合征和败血症）中发挥作用。COVID-19并发症与口腔健康和牙周病之间的联系也得到了研究，因为COVID-19并发症风险最高的合并症也会导致口腔微生物组失衡，增加牙周病的风险。我们探讨了口腔中高细菌载量与病毒感染后并发症之间的联系，以及改善口腔健康如何降低COVID-19并发症的风险。
On 30 January 2020, the World Health Organisation identified COVID-19, caused by the virus SARS-CoV-2, to be a global emergency. The risk factors already identified for developing complications from a COVID-19 infection are age, gender and comorbidities such as diabetes, hypertension, obesity and cardiovascular disease. These risk factors, however, do not account for the other 52% of deaths arising from COVID-19 in often seemingly healthy individuals. This paper investigates the potential link between SARS-CoV-2 and bacterial load, questioning whether bacteria may play a role in bacterial superinfections and complications such as pneumonia, acute respiratory distress syndrome and sepsis. The connection between COVID-19 complications and oral health and periodontal disease is also examined, as the comorbidities at highest risk of COVID-19 complications also cause imbalances in the oral microbiome and increase the risk of periodontal disease. We explore the connection between high bacterial load in the mouth and post-viral complications, and how improving oral health may reduce the risk of complications from COVID-19.