EFFECT OF THE SLT MUTANT ALLELE ON THE PRODUCTION OF TISSUE MAST-CELLS IN MICE
EFFECT OF THE SLT MUTANT ALLELE ON THE PRODUCTION OF TISSUE MAST-CELLS IN MICE
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DOI：
10.1093/oxfordjournals.jhered.a109814
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发表时间：
1983-01-01
影响因子：
3.1
通讯作者：
TUTIKAWA, K
中科院分区：
文献类型：
--
作者：
KOHROGI, T;YOKOYAMA, M;TUTIKAWA, K
比较了SLT突变基因对黑素细胞、组织肥大细胞和红细胞生成的影响，以及在相同遗传背景下SLT突变基因对黑素细胞、组织肥大细胞和红细胞生成的影响。C57BL/6)F1小鼠]。尽管3种细胞(+/+>；SLT/SLT>；SLD/SLT>；SL/SLD)的细胞数等级顺序相似，但黑素细胞的差异最大，红细胞的差异最小。由于雄性SLT/SLT小鼠(在WB和C57BL/6背景上)是可生育的，这些小鼠有助于有效地培育中度肥大细胞缺陷的SL/SLT和SLD/SLT小鼠。
The effect of Slt mutant gene on the production of melanocytes, tissue mast cells and erythrocytes was compared with the effect of the Sl and Sld mutant genes on the same genetic background [(WB .times. C57BL/6)F1 mice]. Although the rank order of cell numbers was similar in these 3 types of cells (i.e., +/+ > Slt/Slt > Sld/Slt > Sl/Slt > Sl/Sld), the difference in the melanocytes was largest, and the difference in the erythrocytes was smallest. Since male Slt/Slt mice (on both WB and C57BL/6 backgrounds) were fertile, such mice were useful for efficient production of moderately mast cell-deficient Sl/Slt and Sld/Slt mice.