French cattle is not a reservoir of the highly virulent enteroaggregative Shiga toxin-producing Escherichia coli of serotype O104:H4
French cattle is not a reservoir of the highly virulent enteroaggregative Shiga toxin-producing Escherichia coli of serotype O104:H4
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DOI：
10.1016/j.vetmic.2012.02.029
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发表时间：
2012-08-17
影响因子：
3.3
通讯作者：
Brugere, Hubert
中科院分区：
文献类型：
--
作者：
Auvray, Frederic;Dilasser, Francoise;Brugere, Hubert
2011年5月至6月，欧洲发生了由产肠聚集性志贺毒素(STX)的大肠杆菌(STEC)O104：H4引起的溶血性尿毒症综合征的大规模暴发，这与食用发芽种子有关。由于反刍动物是STEC的已知宿主，这项研究调查了牛是否可能是肠道聚集性STEC O104：H4的宿主和向人类传播的潜在来源。通过针对stx2、wzx(O104)、flc(H4)和aggR遗传标记的聚合酶链式反应分析了1468头法国牛的粪便携带暴发菌株。没有一份粪便样本同时含有这四种标志物，这表明牛并不是这种新出现的大肠杆菌致病类型的宿主。(C)2012爱思唯尔B.V.保留所有权利。
In May-June 2011, a massive outbreak of haemolytic uraemic syndrome caused by enteroaggregative Shiga toxin (Stx)-producing Escherichia coli (STEC) O104:H4 occurred in Europe, which was linked to the consumption of sprouted seeds. As ruminants are known reservoirs of STEC, this study investigated whether cattle could be a reservoir of enteroaggregative STEC O104:H4 and a potential source of transmission to humans. A total of 1468 French cattle were analysed for faecal carriage of the outbreak strain by PCR assays targeting stx2, wzx(O104), fliC(H4) and aggR genetic markers. None of the faecal samples contained the four markers simultaneously, indicating that cattle is not a reservoir of this recently emerged E. coli pathotype. (C) 2012 Elsevier B.V. All rights reserved.