ISOLATION OF NEW BROMINATED SESQUITERPENE FEEDING DETERRENTS FROM TROPICAL GREEN-ALGA NEOMERIS-ANNULATA (DASYCLADACEAE, CHLOROPHYTA)
ISOLATION OF NEW BROMINATED SESQUITERPENE FEEDING DETERRENTS FROM TROPICAL GREEN-ALGA NEOMERIS-ANNULATA (DASYCLADACEAE, CHLOROPHYTA)
复制标题
DOI：
10.1007/bf00983791
复制
发表时间：
1993-09-01
影响因子：
2.3
通讯作者：
CARDELLINA, JH
中科院分区：
文献类型：
--
作者：
PAUL, VJ;CRONAN, JM;CARDELLINA, JH
我们研究了太平洋地区石灰性热带绿色藻类环新梅藻产生的溴化倍半萜的天然产物化学成分和拒食作用。用全藻进行的分析表明，N。annulata是不容易放牧的自然种群的草食性鱼类在关岛。粗提物和柱层析馏分含有溴化倍半萜阻止进食的草食性鱼类在自然浓度在关岛的现场测定。两个大N从关岛收集物中分离的annulata倍半萜和以前从百慕大报告的三种相关倍半萜在其天然浓度范围的高端都阻止了鱼类摄食，除了一种来自百慕大收集物的代谢物在结构上与其他化合物不同。这些结果支持了我们的假设，即Neomeris产生的化合物起着对抗食草动物的化学防御作用。珊瑚礁产生结构防御（碳酸钙以文石的形式）和次级代谢产物，以抵御珊瑚鱼的食草性。
We investigated the natural products chemistry and feeding deterrent effects of brominated sesquiterpenes produced by Pacific collections of the calcareous tropical green alga Neomeris annulata. Assays conducted with whole algae showed that N. annulata was not susceptible to grazing by natural populations of herbivorous fishes on Guam. Crude extracts and column chromatography fractions containing the brominated sesquiterpenes deterred feeding by herbivorous fishes at natural concentrations in field assays on Guam. Two major N. annulata sesquiterpenes isolated from Guam collections and three related sesquiterpenes previously reported from Bermuda all deterred fish feeding at the high end of their natural concentration ranges, with the exception of one metabolite from Bermuda collections of the alga that differed structurally from the other compounds. The results support our hypothesis that the compounds produced by Neomeris function as chemical defenses against herbivores. The alga produces both structural defenses (CaCO3 in the form of aragonite) and secondary metabolites that defend against herbivory by reef fishes.