Proceedings of the Sleep and Epilepsy Workshop: Section 1 Decreasing Seizures-Improving Sleep and Seizures, Themes for Future Research.

Proceedings of the Sleep and Epilepsy Workshop: Section 1 Decreasing Seizures-Improving Sleep and Seizures, Themes for Future Research.
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DOI:
10.1177/15357597211004566
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发表时间:
2021-03-31
期刊:
影响因子:
3.6
通讯作者:
Buchanan GF
Buchanan GF
中科院分区:
医学3区
文献类型:
--
作者:
Quigg M;Bazil CW;Boly M;St Louis EK;Liu J;Ptacek L;Maganti R;Kalume F;Gluckman BJ;Pathmanathan J;Pavlova MK;Buchanan GF

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癫痫发作,睡眠和昼夜节律的时间共享双边的相互作用,但协调一致的工作,以表征这些相互作用,并利用他们的优势,癫痫患者仍然处于起步阶段。为了进一步推动这一领域的发展,一个由睡眠医生、癫痫学家、昼夜节律计时专家和其他人组成的多学科小组举行了会议,概述了最新技术水平、知识差距,并提出了临床、转化和基础研究的前进方向。一个多学科专家小组讨论了这些相互作用,重点是睡眠或昼夜节律的改善是否会降低癫痫发作频率。此外,患者、其家人和医生缺乏有关睡眠的教育,对教育的关注是一个极其重要的“容易收获的果实”。监测技术的改进,对解剖睡眠与昼夜节律影响所需的严格性敏感的实验设计,以及通过改善睡眠减少癫痫发作的临床试验是合适的。
Epileptic seizures, sleep, and circadian timing share bilateral interactions, but concerted work to characterize these interactions and to leverage them to the advantage of patients with epilepsy remains in beginning stages. To further the field, a multidisciplinary group of sleep physicians, epileptologists, circadian timing experts, and others met to outline the state of the art, gaps of knowledge, and suggest ways forward in clinical, translational, and basic research. A multidisciplinary panel of experts discussed these interactions, centered on whether improvements in sleep or circadian rhythms improve decrease seizure frequency. In addition, education about sleep was lacking in among patients, their families, and physicians, and that focus on education was an extremely important “low hanging fruit” to harvest. Improvements in monitoring technology, experimental designs sensitive to the rigor required to dissect sleep versus circadian influences, and clinical trials in seizure reduction with sleep improvements were appropriate.
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