European guidance for the diagnosis and management of osteoporosis in postmenopausal women

European guidance for the diagnosis and management of osteoporosis in postmenopausal women
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DOI:
10.1007/s00223-018-00512-x
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发表时间:
2019-01-01
影响因子:
4
通讯作者:
Reginster, J. -Y.
Reginster, J. -Y.
中科院分区:
医学2区
文献类型:
--
作者:
Kanis, J. A.;Cooper, C.;Reginster, J. -Y.

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介绍国际骨质疏松基金会和欧洲骨质疏松症和骨关节炎临床与经济方面协会于2013年发布了骨质疏松的诊断和治疗指南。结果:骨密度测量在骨质疏松症诊断和骨折风险评估中的作用;骨质疏松的一般和药物管理;治疗监测;骨折风险评估;病例发现策略;患者调查;治疗的卫生经济学。最新信息包括骨折风险评估中骨微结构评估的评估,FRAX(R)和骨折联络服务在二次骨折预防中的作用,饮食摄入对骨折风险的长期影响,以及停止药物治疗增加骨折风险。
Guidance is provided in a European setting on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis.IntroductionThe International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2013. This manuscript updates these in a European setting.MethodsSystematic reviews were updated.ResultsThe following areas are reviewed: the role of bone mineral density measurement for the diagnosis of osteoporosis and assessment of fracture risk; general and pharmacological management of osteoporosis; monitoring of treatment; assessment of fracture risk; case-finding strategies; investigation of patients; health economics of treatment. The update includes new information on the evaluation of bone microstructure evaluation in facture risk assessment, the role of FRAX (R) and Fracture Liaison Services in secondary fracture prevention, long-term effects on fracture risk of dietary intakes, and increased fracture risk on stopping drug treatment.ConclusionsA platform is provided on which specific guidelines can be developed for national use.