CAMPYLOBACTER COLITIS
CAMPYLOBACTER COLITIS
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DOI：
10.1136/bmj.1.6167.857
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发表时间：
1979-01-01
影响因子：
--
通讯作者：
MANDAL, BK
中科院分区：
文献类型：
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作者：
LAMBERT, ME;SCHOFIELD, PF;MANDAL, BK
连续11例腹泻患者的粪便中分离出弯曲杆菌，通过乙状结肠镜检查和直肠活检进行了研究。8例明确的直肠炎，7例活检标本异常，组织学变化范围从非特异性结肠炎到肉眼结肠炎，伴有杯状细胞耗竭和隐窝脓肿形成。其中九名患者的粪便中带有血，除了一名患者外，所有患者的腹痛都是这种疾病的特征。严重的弯曲杆菌性结肠炎在临床上、乙状结肠镜下和组织学上可能难以与溃疡性结肠炎鉴别，并且是急性结肠炎的鉴别诊断。
Eleven consecutive patients with diarrhoea from whose stools campylobacter were isolated were investigated by sigmoidoscopy and rectal biopsy. Eight had definite proctitis, and in seven biopsy specimens were abnormal with histological changes ranging from non-specific colitis to gross colitis with goblet-cell depletion and crypt-abscess formation. Nine of the patients passed blood in their stools, and in all but one abdominal pain was a feature of the illness. Severe campylobacter colitis may be clinically, sigmoidoscopically, and histologically difficult to differentiate from ulcerative colitis and is a differential diagnosis in acute colitis.