LOCALIZATION OF FIBRONECTIN DURING DENTINOGENESIS IN RAT INCISOR
LOCALIZATION OF FIBRONECTIN DURING DENTINOGENESIS IN RAT INCISOR
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DOI：
10.1016/0003-9969(82)90013-9
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发表时间：
1982-01-01
影响因子：
3
通讯作者：
JONTELL, M
中科院分区：
文献类型：
--
作者：
LINDE, A;JOHANSSON, S;JONTELL, M
用间接免疫荧光法检测了牙本质形成不同阶段牙髓和前牙本质中纤维连接蛋白(FN)的表达。FN存在于内釉上皮和牙间充质之间的基底膜以及套层前牙本质中。在进一步的(围蛹)牙本质形成过程中，前牙本质中没有FN，这表明FN分子不直接参与矿化。这些发现强调了外套膜和牙髓周围牙本质形成的不同。FN定位于成牙本质细胞层中，位于细胞突起离开细胞体和成牙本质细胞通过连接复合体相互粘连的水平。
Fibronectin (FN) was localized in the dental pulp and predentine at different stages of dentinogenesis by indirect immunofluorescence. FN was present in the basement membrane between the inner enamel epithelium and the underlying dental mesenchyme as well as in mantle predentine. FN was absent from predentine during further (circumpupal) dentine formation, indicating that the FN molecule is not directly involved in mineralization. The findings emphasize the difference between the mantle and circumpulpal dentine formation. FN was localized in the odontoblast layer at the level where the cell processes leave the cell bodies and where the odontoblasts adhere to each other by junctional complexes.