Mechanical Thrombectomy for Acute Ischemic Stroke Amid the COVID-19 Outbreak Decreased Activity, and Increased Care Delays
Mechanical Thrombectomy for Acute Ischemic Stroke Amid the COVID-19 Outbreak Decreased Activity, and Increased Care Delays
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DOI：
10.1161/strokeaha.120.030373
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发表时间：
2020-07-01
期刊：
影响因子：
8.3
通讯作者：
Boulouis, Gregoire
中科院分区：
文献类型：
--
作者：
Kerleroux, Basile;Fabacher, Thibaut;Boulouis, Gregoire
背景和目的：在2019冠状病毒病（COVID-19）爆发期间，院前护理链响应的效率和医院资源的充足性受到挑战，对符合机械血栓切除术（MT）的缺血性卒中患者产生了疑似后果。研究方法：我们对接受MT治疗的患者进行了前瞻性的国家级数据收集，范围为流行病控制措施恢复期间的45天，以及2019年同一日历期间接受治疗的患者。主要终点是流行期间接受MT的患者的变化。次要终点包括发病、影像学检查和腹股沟穿刺之间的护理延迟。为了分析主要终点，我们使用Poisson回归模型。然后，我们使用Pearson相关系数（与空值相比）分析了MT数量与COVID-19病例住院数量之间的相关性。结果：在法国所有行政区域的32个中心共纳入1513例患者。有21%的显著性下降（0.79; [95%CI，0.76-0.82];P
Background and Purpose: The efficiency of prehospital care chain response and the adequacy of hospital resources are challenged amid the coronavirus disease 2019 (COVID-19) outbreak, with suspected consequences for patients with ischemic stroke eligible for mechanical thrombectomy (MT). Methods: We conducted a prospective national-level data collection of patients treated with MT, ranging 45 days across epidemic containment measures instatement, and of patients treated during the same calendar period in 2019. The primary end point was the variation of patients receiving MT during the epidemic period. Secondary end points included care delays between onset, imaging, and groin puncture. To analyze the primary end point, we used a Poisson regression model. We then analyzed the correlation between the number of MTs and the number of COVID-19 cases hospitalizations, using the Pearson correlation coefficient (compared with the null value). Results: A total of 1513 patients were included at 32 centers, in all French administrative regions. There was a 21% significant decrease (0.79; [95%CI, 0.76-0.82];P