How Many Phosphoric Acid Units Are Required to Ensure Uniform Occlusion of Sterically Stabilized Nanoparticles within Calcite?
How Many Phosphoric Acid Units Are Required to Ensure Uniform Occlusion of Sterically Stabilized Nanoparticles within Calcite?
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DOI：
10.1002/anie.201901307
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发表时间：
2019-06-24
影响因子：
16.6
通讯作者：
Armes, Steven P.
中科院分区：
文献类型：
--
作者：
Douverne, Marcel;Ning, Yin;Armes, Steven P.
由可逆加成-破碎链转移（RAFT）聚合介导的聚合诱导自组装（PISA）为高效、通用地合成良好定义的立体稳定嵌段共聚物纳米颗粒提供了平台技术。本文通过阴离子2-（磷酸氧基）甲基丙烯酸乙酯(P)与非离子单甲基丙烯酸甘油(G)的统计共聚制备了一系列具有可调阴离子电荷密度的纳米颗粒。P/G摩尔比的系统变化能够阐明促进模型无机晶体（方解石）内纳米颗粒咬合所需的每个共聚物链的最小磷酸基团数量。此外，纳米颗粒的遮挡程度与空间稳定链的磷酸盐含量密切相关。本研究首次研究了系统地改变纳米颗粒的阴离子电荷密度对其遮挡效率的影响，并为最大化方解石宿主晶体内客体纳米颗粒的负载提供了新的思路。
Polymerization-induced self-assembly (PISA) mediated by reversible addition-fragmentation chain transfer (RAFT) polymerization offers a platform technology for the efficient and versatile synthesis of well-defined sterically stabilized block copolymer nanoparticles. Herein we synthesize a series of such nanoparticles with tunable anionic charge density within the stabilizer chains, which are prepared via statistical copolymerization of anionic 2-(phosphonooxy)ethyl methacrylate (P) with non-ionic glycerol monomethacrylate (G). Systematic variation of the P/G molar ratio enables elucidation of the minimum number of phosphate groups per copolymer chain required to promote nanoparticle occlusion within a model inorganic crystal (calcite). Moreover, the extent of nanoparticle occlusion correlates strongly with the phosphate content of the steric stabilizer chains. This study is the first to examine the effect of systemically varying the anionic charge density of nanoparticles on their occlusion efficiency and sheds new light on maximizing the loading of guest nanoparticles within calcite host crystals.