Hypothyroidism
Hypothyroidism
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DOI：
10.1542/pir.35-8-336
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发表时间：
2014-08-01
影响因子：
1.3
通讯作者：
Diaz, Elizabeth G. Lipman
中科院分区：
文献类型：
--
作者：
Diaz, Alejandro;Diaz, Elizabeth G. Lipman
先天性甲状腺功能减退症是可预防的智力残疾的最常见原因之一。意识到并不是所有的情况下发现的新生儿筛查是很重要的，特别是因为早期诊断和治疗是必不可少的，在保存cognitive abilities.Objectives完成这篇文章后，读者应该能够：1.确定婴儿和儿童先天性和后天性甲状腺功能减退症的原因。2.解释异常新生儿筛查结果，了解进一步评估和治疗的指征.识别甲状腺功能减退症的临床体征和症状。4.了解先天性甲状腺功能减退症早期诊断和治疗的重要性.了解桥本甲状腺炎的临床表现、诊断过程、治疗及预后.甲状腺结合球蛋白缺乏症与中枢性甲状腺功能减退症的鉴别。7.确定病态甲状腺功能正常综合征和其他原因的甲状腺功能异常测试结果。
Congenital hypothyroidism is one the most common causes of preventable intellectual disability. Awareness that not all cases are detected by the newborn screening is important, particularly because early diagnosis and treatment are essential in preserving cognitive abilities.Objectives After completing this article, readers should be able to:1. Identify the causes of congenital and acquired hypothyroidism in infants and children.2. Interpret an abnormal newborn screening result and understand indications for further evaluation and treatment.3. Recognize clinical signs and symptoms of hypothyroidism.4. Understand the importance of early diagnosis and treatment of congenital hypothyroidism.5. Understand the presentation, diagnostic process, treatment, and prognosis of Hashimoto thyroiditis.6. Differentiate thyroid-binding globulin deficiency from central hypothyroidism. 7. Identify sick euthyroid syndrome and other causes of abnormal thyroid function test results.