Enhanced Chemical Sensing with Multiorder Coherent Raman Scattering Spectroscopic Dephasing.
Enhanced Chemical Sensing with Multiorder Coherent Raman Scattering Spectroscopic Dephasing.
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DOI：
10.1021/acs.analchem.2c01060
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发表时间：
2022-06-14
影响因子：
7.4
通讯作者：
Zhang, Delong
中科院分区：
文献类型：
--
作者：
Zhu, Hanlin;Xu, Chenran;Wang, Da-Wei;Yakovlev, Vladislav V.;Zhang, Delong
分子振动光谱学广泛应用于各种传感和成像应用，提供分子水平上的内在信息。利用超短激光脉冲的非线性光相互作用，通过将能量聚焦到特定的分子键上，促进了分子振动模式的选择性相干激发，将信号水平提高了多个数量级。然而，这种相干性的消相，容易受到局部分子环境的影响，往往被忽视。振动减相动力学的独特能力，作为复杂分子相互作用和局部纳米和微环境影响的独特探针，是传统的基于强度的光谱学所无法达到的。在这里，我们开发了一种新的多阶相干拉曼光谱平台，特别关注分子振动减相的时间演化，称为时间分辨相干拉曼散射（T-CRS）光谱。通过利用高动态范围检测，分子振动动力学和环境效应被多维光谱传感证明，这在生物、材料和化学科学中有新的应用范围。
Molecular vibrational spectroscopy is widely used in various sensing and imaging applications, providing intrinsic information at the molecular level. Nonlinear optical interactions using ultrashort laser pulses facilitate the selective coherent excitation of molecular vibrational modes by focusing energy into specific molecular bonds, boosting the signal level for multiple orders of magnitude. The dephasing of such coherence, which is susceptible to the local molecular environment, however, is often neglected. The unique capability of vibrational dephasing dynamics to serve as a unique probe for complex molecular interactions and the effect of local nano- and microenvironments are beyond the reach of conventional, intensity-based spectroscopy. Here, we developed a novel multiorder coherent Raman spectroscopy platform with a special focus on the temporal evolution of molecular vibrational dephasing, termed as time-resolved coherent Raman scattering (T-CRS) spectroscopy. By utilizing a high dynamic range detection, molecular vibrational dynamics and the environmental effects are demonstrated with multidimensional spectroscopic sensing, which promises a new range of applications in biology, materials, and chemical sciences.
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影响因子：
15
作者：
Frontiera, Renee R.;Dasgupta, Jyotishman;Mathies, Richard A.
通讯作者：
Mathies, Richard A.
DOI：
10.1073/pnas.0708425104
发表时间：
2007-12-04
影响因子：
11.1
作者：
Skala, Melissa C.;Riching, Kristin M.;Ramanujam, Nirmala
通讯作者：
Ramanujam, Nirmala
影响因子：
2.8
作者：
OKAMOTO, H;YOSHIHARA, K
通讯作者：
YOSHIHARA, K
影响因子：
3.3
作者：
Sturlaugson, Adam L.;Fruchey, Kendall S.;Fayer, Michael D.
通讯作者：
Fayer, Michael D.
影响因子：
3.8
作者：
Petrov, Georgi I.;Meng, Zhaokai;Yakovlev, Vladislav V.
通讯作者：
Yakovlev, Vladislav V.