Do Patients with Chronic Spinal Pain and Comorbid Insomnia Have More Features of Central Sensitization? A Case-Control Study.
Do Patients with Chronic Spinal Pain and Comorbid Insomnia Have More Features of Central Sensitization? A Case-Control Study.
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DOI：
10.3390/healthcare11243152
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发表时间：
2023-12-12
期刊：
影响因子：
2.8
通讯作者：
De Baets, Liesbet
中科院分区：
文献类型：
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作者：
Araujo Almeida, Lucas;Bilterys, Thomas;Van Looveren, Eveline;Mairesse, Olivier;Cagnie, Barbara;Meeus, Mira;Moens, Maarten;Goubert, Dorien;Munneke, Wouter;Danneels, Lieven;Ickmans, Kelly;Rezende Camargo, Paula;Nijs, Jo;Malfliet, Anneleen;De Baets, Liesbet
背景：慢性脊柱疼痛（CSP）是世界范围内的一个主要公共卫生问题，通常与睡眠问题有关。中枢敏化（CS）可能会使伴有失眠的 CSP 患者的临床表现恶化。本研究的目的是比较伴有和不伴有 CS 症状的共病失眠的失眠 CSP 患者的自我报告和客观测量的临床结果。方法：通过在线调查问卷对基线自我报告的睡眠、功能和心理困扰进行病例对照研究。分别通过多导睡眠图、体动记录仪和数字测痛法评估客观睡眠和身体活动参数以及压痛阈值（PPT）。独立样本 t 检验和曼-惠特尼 U 检验用于检查各组之间结果测量可能存在的差异。结果：纳入了 123 名参与者的数据，显示客观睡眠和体力活动参数没有统计学显着性。然而，CS 组的自我报告睡眠较差（睡眠质量、失眠严重程度和对睡眠的信念失调）、精神和身体疲劳增加、心理困扰（焦虑和抑郁症状）较高，并且报告的 PPT 较低。结论：CS 症状可能影响感知睡眠并影响功能健康和幸福感，但似乎不影响客观睡眠和身体活动。
Background: Chronic spinal pain (CSP) is a major public health problem worldwide, frequently related to sleep problems. Central sensitization (CS) may worsen the clinical picture of CSP patients with insomnia. The aim of this study was to compare self-reported and objectively measured clinical outcomes between insomniac CSP patients with comorbid insomnia with and without symptoms of CS. Methods: A case-control study on baseline self-reported sleep, functioning, and psychological distress through online questionnaires. Objective sleep and physical activity parameters and pressure pain thresholds (PPTs) were assessed through polysomnography, actigraphy, and digital algometry, respectively. Independent sample t-test and Mann–Whitney U tests were used to examine possible differences in the outcome measures between the groups. Results: Data from 123 participants were included and revealed no statistically significant group for objective sleep and physical activity parameters. The CS group, however, presented with worse self-reported sleep (quality sleep, insomnia severity, and dysfunctional beliefs about sleep), increased mental and physical fatigue, and higher psychological distress (anxiety and depressive symptoms), and reported lower PPTs. Conclusions: symptoms of CS may influence perceived sleep and affect functional health and well-being perception but do not seem to affect objective sleep and physical activity.
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DOI：
10.3390/ijerph18031082
发表时间：
2021-01-26
影响因子：
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作者：
Fabbri M;Beracci A;Martoni M;Meneo D;Tonetti L;Natale V
通讯作者：
Natale V
DOI：
10.3122/jabfm.2013.06.130064
发表时间：
2013-11-01
影响因子：
2.9
作者：
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通讯作者：
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影响因子：
3.4
作者：
Aili, Katarina;Nyman, Teresia;Svartengren, Magnus
通讯作者：
Svartengren, Magnus
影响因子：
4.8
作者：
Bastien, Celyne H.;Vallieres, Annie;Morin, Charles M.
通讯作者：
Morin, Charles M.
DOI：
10.1080/10401230701468099
发表时间：
2007-07-01
期刊：
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
影响因子：
--
作者：
Blay, Sergio Luis;Andreoli, Sergio Baxter;Gastal, Fabio Leite
通讯作者：
Gastal, Fabio Leite