Controlling vesicle formation via interpolymer hydrogen-bonding complexation between poly(ethylene oxide)-block-polybutadiene and poly(acrylic acid) in solution
Controlling vesicle formation via interpolymer hydrogen-bonding complexation between poly(ethylene oxide)-block-polybutadiene and poly(acrylic acid) in solution
复制标题
通过溶液中聚环氧乙烷-嵌段聚丁二烯和聚丙烯酸之间的互聚物氢键络合控制囊泡的形成
DOI：
10.1021/ma0603579
复制
发表时间：
2006-07-11
期刊：
影响因子：
5.5
通讯作者：
Zhou, Qi-Feng
中科院分区：
文献类型：
--
作者：
Gao, Wei-Ping;Bai, Yu;Zhou, Qi-Feng
This paper describes a controllable vesicle formation of a diblock copolymer of poly(ethylene oxide)-block-polybutadiene (PEO-b-PB) and a homopolymer of poly(acrylic acid) (PAA) in a solvent mixture of THF and n-dodecane. The number-average molecular weights (Mn) of both the PEO and PB blocks are 5100 g/mol; the weight-average molecular weight (Mw) of the PAA is ∼2000 g/mol. The assembly is driven by the hydrogen-bonding complexation between the complementary binding sites on PEO and PAA. The vesicles can load PAA far above the stoichiometrical monomer ratio of PAA to PEO ([AA]/[EO]). At 0.85 ≤ [AA]/[EO] ≤ 2.5, unilamellar vesicles (ULVs) with a constant membrane thickness of 16 nm are obtained in a controllable manner, of which the surface area increases linearly with [AA]/[EO]. Further increasing [AA]/[EO] above 3 results in the formation of multivesicular vesicles (MVVs). The PAA chains in ULVs are uniformly inserted into membranes with a direction preferentially perpendicular to the interface. When th...
