Influence of chemical immobilization and physical restraint on steroid hormone levels in blood of white-tailed deer.
Influence of chemical immobilization and physical restraint on steroid hormone levels in blood of white-tailed deer.
复制标题
化学固定和物理约束对白尾鹿血液中类固醇激素水平的影响。
DOI：
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发表时间：
1979
影响因子：
1.4
通讯作者：
R. Butcher
中科院分区：
文献类型：
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作者：
J. Wesson;P. Scanlon;R. L. Kirkpatrick;H. S. Mosby;R. Butcher
本研究的结果提供了证据，证明在采血前或采血期间，由于束缚方法，某些血液内分泌测量值发生了变化。三种化学约束剂，其生理效应，作用方式和管理方法有很大的不同，在白尾鹿进行了检查。使用的药物是氯化琥珀胆碱（SCC）、RO-5-3448以及盐酸苯环利定（PH）和镇静剂盐酸丙嗪（P）的组合。此外，还检查了在不给药的情况下手动约束的效果。所有的鹿都在药物和（或）手动约束的影响下重复流血的。SCC和手动约束似乎引起了最大的报警鹿，并导致肾上腺皮质激素和孕激素的最高水平。孕激素的增加似乎在某种程度上是由肾上腺产生的。RO-5-3448和PH + P能降低藻细胞的活性。
The results of this investigation provided evidence for changes in certain blood endocrine measurements immediately prior to, or during, blood collection as a result of the method of restraint. Three chemical restraint agents which differed widely in their physiological effects, mode of action, and method of administration were examined in white-tailed deer. The drugs employed were succinylcholine chloride (SCC), RO-5-3448, and a combination of phencyclidine hydrochloride (PH) and the tranquilizer promazine hydrochloride (P). In addition, the effects of manual restraint without drug administration were examined. All deer were repetitively bled while under the influence of a drug and (or) manual restraint. SCC and manual restraint appeared to elicit the greatest alarm by the deer and resulted in the highest levels of adrenocorticoids and progestins. It appeared likely that the increase in progestins resulted in some way from production by the adrenal glands. RO-5-3448 and PH + P appeared to decrease the al...