LEISHMANIASIS IN TEXAS - PREVALENCE AND SEASONAL TRANSMISSION OF LEISHMANIA-MEXICANA IN NEOTOMA-MICROPUS
LEISHMANIASIS IN TEXAS - PREVALENCE AND SEASONAL TRANSMISSION OF LEISHMANIA-MEXICANA IN NEOTOMA-MICROPUS
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DOI：
10.4269/ajtmh.1995.53.73
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发表时间：
1995-07-01
影响因子：
3.3
通讯作者：
DRONEN, NO
中科院分区：
文献类型：
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作者：
KERR, SF;MCHUGH, CP;DRONEN, NO
通过筛选192个N.用离体培养的方法培养小孢子。8只林鼠也进行了筛选，使用聚合酶链反应（PCR）。还测试了来自4个地点的46个Sigmodon hispidus。季节性传播进行了调查，通过在三个地点的陷阱，重捕研究和青少年感染的分析。十四N。4个地区的小蚤L.墨西哥，表明这些地区的年流行率为5.6- 27%，并非零。仅通过PCR检测到两个病灶处的四个额外感染。在每种情况下，传播发生在秋季，可以确定传播季节。没有S。hispidus阳性。这些数据支持了N. micropus是L.德克萨斯州的墨西哥
The annual prevalence of Leishmania mexicana in Neotoma micropus from 16 southern Texas localities was determined by screening 192 N. micropus using in vitro culture. Eight woodrats also were screened using the polymerase chain reaction (PCR). Forty-six Sigmodon hispidus from four localities were also tested. Seasonal transmission was investigated through trap-recapture studies at three localities and analysis of infections in juveniles. Fourteen N. micropus from four localities were culture-positive for L. mexicana, indicating an annual non-zero prevalence at these localities of 5.6-27%. Four additional infections at two foci were detected only by the PCR. Transmission occurred in the fall in each case in which season of transmission could be determined. No S. hispidus were positive. These data support the hypothesis that N. micropus is a reservoir of L. mexicana in Texas.