The role of integrins in tumor angiogenesis
The role of integrins in tumor angiogenesis
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DOI：
10.1016/j.hoc.2004.09.010
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发表时间：
2004-10-01
影响因子：
2.4
通讯作者：
Varner, J
中科院分区：
文献类型：
--
作者：
Hwang, R;Varner, J
Integrins are cell adhesion molecules that play an important role in the regulation of angiogenesis. In this overview, the vascular integrins and their mechanisms of action are outlined. Integrins have been evaluated in preclinical and clinical studies for the treatment of cancer and as diagnostic markers of angiogenesis. Furthermore, integrins are the basis for targeted therapy for solid tumors and novel imaging techniques to assess the angiogenic response of tumors.
