COMPARATIVE FIELD-EVALUATION OF THE FLUORESCENT-ANTIBODY TEST, VIRUS ISOLATION FROM TISSUE-CULTURE, AND ENZYME IMMUNODIAGNOSIS FOR RAPID LABORATORY DIAGNOSIS OF RABIES
COMPARATIVE FIELD-EVALUATION OF THE FLUORESCENT-ANTIBODY TEST, VIRUS ISOLATION FROM TISSUE-CULTURE, AND ENZYME IMMUNODIAGNOSIS FOR RAPID LABORATORY DIAGNOSIS OF RABIES
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DOI：
10.1128/jcm.27.3.519-523.1989
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发表时间：
1989-03-01
影响因子：
9.4
通讯作者：
SUREAU, P
中科院分区：
文献类型：
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作者：
BOURHY, H;ROLLIN, PE;SUREAU, P
本文对狂犬病组织培养感染试验（RTCIT）和狂犬病酶免疫快速诊断（RREID）与荧光抗体试验（FAT）进行了比较。在法国国家狂犬病参考中心，通过FAT和RTCIT分析了15，248份标本，其中2，290份标本还通过RREID进行了检测;在非洲、亚洲和拉丁美洲的12个实验室中，通过FAT和RREID检测了818份其他标本。RREID和RTCIT的敏感性和特异性相当。这项研究表明，这两种测试可以作为备份程序，以确认脂肪。RREID也强烈建议用于流行病学研究和没有进行FAT设备的实验室。
The rabies tissue culture infection test (RTCIT) and rapid rabies enzyme immunodiagnosis (RREID) were compared to the fluorescent-antibody test (FAT) with field speicmens. At the French National Reference Center for Rabies, 15,248 specimens were analyzed by FAT and RTCIT, and 2,290 of those specimens were also tested by RREID; 818 other specimens were tested by FAT and RREID in 12 laboratories located in Africa, Asia, and Latin America. The sensitivities and specificities of RREID and RTCIT were comparable. This study showed that both tests can be used as backup procedures to confirm FAT. RREID is also strongly recommended for epidemiological studies and for laboratories which are not equipped for performing FAT.