Fatigue and quality of life outcomes of exercise during cancer treatment
Fatigue and quality of life outcomes of exercise during cancer treatment
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DOI：
10.1046/j.1523-5394.2001.009003119.x
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发表时间：
2001-05-01
期刊：
影响因子：
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通讯作者：
McCorkle, R
中科院分区：
文献类型：
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作者：
Mock, V;Pickett, M;McCorkle, R
目的：尽管认识到疲劳是癌症治疗过程中常见和令人痛苦的症状，但很少有基于证据的干预措施可用于管理这种疲劳。本多机构试点研究的目的是探讨影响的家庭为基础的适度步行锻炼干预对疲劳，身体功能，情绪困扰，和生活质量（QOL）在乳腺癌treatment.Description研究：52名妇女被招募从五所大学医院门诊部本试点研究与实验设计。受试者在乳腺癌辅助化疗或放疗期间被随机分配到步行计划或常规护理。症状，身体功能，和生活质量进行了测量，在基线，治疗中期，并在治疗结束时。结果：妇女谁行使至少90分钟，每周3天或以上的报告显着减少疲劳和情绪困扰，以及较高的功能能力和生活质量比妇女谁是在治疗期间不太活跃。临床意义：在家步行锻炼计划是一种潜在有效、低成本且安全的干预措施，可以在乳腺癌辅助化疗或放疗期间管理疲劳并改善生活质量。这种促进健康的自我保健活动需要在大型随机临床试验中进一步测试。
Purpose: Despite the recognition of fatigue as a common and distressing symptom during cancer treatment, there are few evidence-based interventions available to manage such fatigue. The purpose of this multi-institutional pilot study was to explore the effects of a home-based moderate walking exercise intervention on fatigue, physical functioning, emotional distress, and quality of life (QOL) during breast cancer treatment.Description of Study: Fifty-two women were recruited from five university hospital outpatient departments for this pilot study with an experimental design. Subjects were randomly assigned to the walking program or to usual care during adjuvant chemotherapy or radiation therapy for breast cancer. Symptoms, physical functioning, and QOL were measured at baseline, midtreatment, and at the end of the treatment.Results: Women who exercised at least 90 minutes per week on 3 or more days reported significantly less fatigue and emotional distress as well as higher functional ability and QOL than women who were less active during treatment.Clinical Implications: A home-based walking exercise program is a potentially effective, low-cost, and safe intervention to manage fatigue and to improve QOL during adjuvant chemotherapy or radiation therapy for brest cancer. This health-promoting self-care activity needs further testing in large randomized clinical trials.