Robert Clark, Naohiro Ogawa and Andrew Mason (eds), Population Aging, Intergenerational Transfers and the Macroeconomy , Edward Elgar, Cheltenham, Gloucestershire, 2007, 320 pp., hbk £69.95, ISBN 13: 978 1 84720 099 0.
Robert Clark, Naohiro Ogawa and Andrew Mason (eds), Population Aging, Intergenerational Transfers and the Macroeconomy , Edward Elgar, Cheltenham, Gloucestershire, 2007, 320 pp., hbk £69.95, ISBN 13: 978 1 84720 099 0.
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罗伯特·克拉克、小川直宏和安德鲁·梅森（编），《人口老龄化、代际转移和宏观经济》，爱德华·埃尔加，格洛斯特郡切尔滕纳姆，2007 年，320 页，hbk £69.95，ISBN 13：978 1 84720 099 0。
DOI：
10.1017/s0144686x08007575
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发表时间：
2008
影响因子：
2.5
通讯作者：
J. Winter
中科院分区：
文献类型：
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作者：
J. Winter
旨在老年病学家和阅读容易需要一些科学知识的背景。所涵盖的主题包括细胞因子及其在衰老中的作用，遗传学和热量限制在延长寿命，代谢综合征，骨质疏松症，骨关节炎，虚弱，癌症和痴呆症（由Peter Davies撰写）。我发现关于骨质疏松症和骨关节炎的文章非常有用。同样，细胞因子部分也是对该领域的精彩回顾。这本书中一个特别具有挑战性和令人愉快的部分是关于“互动疗法对老龄化人口的重要意义”的章节。虽然我并不同意作者的所有结论，但这一部分无疑为老年病学家应该如何理解和管理复杂的衰老综合征提供了一个蓝图。作为一名老年病学家，我发现他对他汀类药物的颂扬有点令人不安。关于噻唑烷二酮类的章节是在罗格列酮产生潜在心血管损害的证据积累之前撰写的。我个人的偏见会对合成代谢类固醇有更积极的看法，特别是当我们看到选择性雄激素受体分子令人兴奋的发展时。这本书的目的是提供老年医学家与老龄化和疾病的基础科学的见解。它肯定会导致老年病学家想要阅读更多关于这些主题的内容。这本书的一个主要问题是缺乏编辑。在许多情况下，评论或文章的进一步信息应该被脚注或放在文本末尾的注释书目中。"分子生物学概念介绍"部分（E.理查德·斯坦利）未能解决老龄化问题，很难理解，也没有在文本中增加任何内容。同样，复制的数字在黑色和白色和彩色增加了什么，几乎肯定增加了成本的书。总的来说，我对收藏很感兴趣。然而，要从这本书中受益，读者需要有很强的科学背景和对老年医学中遇到的临床问题的广泛知识。
aimed at geriatricians and to read easily requires some background of scientific knowledge. The topics covered include cytokines and their role in ageing, genetics and caloric restriction in extending lifespan, the metabolic syndrome, osteoporosis, osteoarthritis, frailty, cancer and dementia (written by Peter Davies). I found the pieces on osteoporosis and osteoarthritis extremely useful. Similarly the cytokine section was an excellent review of this area. A particularly challenging and enjoyable section of the book was the chapter on ‘Interactive therapies significant for an aging population’. While I did not agree with all the author’s conclusions, this section certainly provides a blueprint for how geriatricians should approach the understanding and management of complex ageing syndromes. As a geriatrician, I found his eulogy for statins a bit unsettling. The section on thiazolidinediones was written before the accumulating evidence of potential cardiovascular damage produced by rosiglitazone. My personal bias would have had a more positive view of anabolic steroids, particularly as we watch the exciting development of selective androgen receptor molecules. This book aims to provide geriatricians with insights into the basic science of ageing and disease. It certainly should result in geriatricians wanting to read more about the topics. A major problem with the book is a lack of editing. There are multiple instances where reviews or articles for further information should have either been footnoted or placed in an annotated bibliography at the end of the text. The section on ‘An introduction to concepts of molecular biology’ (by E. Richard Stanley) failed to address ageing, was difficult to follow, and added nothing to the text. Similarly, the reproduction of the figures in both black and white and colour added nothing and almost certainly increased the cost of the book. Overall, I found much of interest in the collection. To benefit from this book, however, a reader needs a strong science background and a broad knowledge of the clinical problems encountered in geriatrics.