Virtual vortex gear: Unique flow patterns driven by microfluidic inertia leading to pinpoint injection
Virtual vortex gear: Unique flow patterns driven by microfluidic inertia leading to pinpoint injection
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DOI：
10.1063/1.5031082
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发表时间：
2018-05-01
期刊：
影响因子：
3.2
通讯作者：
Kaneko, Makoto
中科院分区：
文献类型：
--
作者：
Tsai, Chia-Hung Dylan;Takayama, Toshio;Kaneko, Makoto
本文研究了微流控芯片上连续产生旋涡的有趣现象。每两个相邻涡流的方向是相反的，就像一组齿轮一样，因此被称为虚拟涡旋齿轮。为了弄清VVG的形成机理，进行了实验和计算模拟。实验结果表明，只有来自某一特定点的气流才会形成旋涡并进入靶室。基于这一现象，提出了一种反映射技术，并证明了只需一次精确的喷射就足以控制微流体室的内容物。VVG可以显著减少生物研究中的化学使用量，并具有其他芯片应用的潜力，如混合和阀门。由AIP出版公司出版。
An interesting phenomenon that vortices are sequentially generated on a microfluidic chip is investigated in this paper. The direction of every two adjacent vortices is opposite to each other, like a set of gears, and thus is named virtual vortex gear (VVG). Both experiments and computational simulations were conducted in order to make clear the mechanism of VVG. The experimental results show that only the flow from a particular point would form vortices and enter the target chamber. A technique of inverse mapping is proposed based on the phenomenon and it demonstrates that only a pinpoint injection is sufficient to control the contents of a microfluidic chamber. VVG can significantly reduce the volume of chemical usage in biological research and has potential for other on-chip applications, such as mixing and valving. Published by AIP Publishing.