A resistance of head lice (Pediculus capitis) to permethrin in Czech Republic.
A resistance of head lice (Pediculus capitis) to permethrin in Czech Republic.
复制标题
捷克共和国头虱（头虱）对氯菊酯产生抗药性。
DOI：
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发表时间：
1995
影响因子：
1.2
通讯作者：
J. Zelenkova
中科院分区：
文献类型：
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作者：
V. Rupeš;J. Moravec;J. Chmela;J. Ledvinka;J. Zelenkova
1992年，捷克共和国的小学爆发了一次虱病。在一些学校，几乎有20%的儿童受到感染。这次暴发可归因于头虱对氯菊酯的抗性，这在文献中尚未提及。在三个城镇建立的LC 50和LC 90值的抗性因子分别在2和385之间和5和557之间。自1978年以来，在捷克共和国仅使用拟除虫菊酯洗剂和洗发水后，这种抗药性逐渐形成，并伴随着对右旋苯醚菊酯和生物烯菊酯的交叉抗药性。但1992年的头虱对马拉硫磷和甲基嘧啶的敏感性与1981年的结果非常相似。含有0.3%马拉硫磷的洗剂（Diffusil H92 M）对抗药性虱子完全有效。当引入实践时，它迅速减少了小学儿童的感染。另外，分别含有0.3%和0.7%的甲基吡嘧磺隆的洗剂和洗发剂也被发现是有效的。
An outbreak of pediculosis at primary schools was recorded in the Czech Republic in 1992. Almost 20% of children in some schools were infested. This outbreak can be attributed to the resistance of head lice to permethrin, which has not been mentioned in literature yet. The resistance factors established in three towns range between 2 and 385 and between 5 and 557 for LC50 and LC90 values, respectively. This resistance has developed after exclusive use of pyrethroids lotion and shampoo in the Czech Republic since 1978, and it was accompanied by a cross-resistance to d-phenothrin and bioalethrin. But the susceptibility of head lice to malathion and pirimiphos-methyl in 1992 was very similar to that found in 1981. The lotion containing 0.3% of malathion (Diffusil H92 M) has been fully effective against the resistant lice. When introduced into the practice, it quickly reduced the infestation of children in primary schools. The other lotion and shampoo containing 0.3% and 0.7% of pirimiphos-methyl respectively were found to be effective as well.