Association of herpes zoster ophthalmicus with acquired immunodeficiency syndrome and acute retinal necrosis.
Association of herpes zoster ophthalmicus with acquired immunodeficiency syndrome and acute retinal necrosis.
复制标题
眼部带状疱疹与获得性免疫缺陷综合征和急性视网膜坏死的关联。
DOI：
10.1016/s0002-9394(14)71346-7
复制
发表时间：
1993
影响因子：
4.2
通讯作者：
Davis,JL
中科院分区：
文献类型：
--
作者：
Sellitti,TP;Huang,AJ;Schiffman,J;Davis,JL
我们进行了一项综述，以调查人类免疫缺陷病毒（HIV）或获得性免疫缺陷综合征（AIDS）在带状疱疹患者中的患病率，以及带状疱疹后急性视网膜坏死的发生率。我们回顾了1987年至1992年间在我们机构就诊的初步诊断为带状疱疹性眼疱疹的所有患者的病历。在112例带状疱疹患者中，29例（26%）患有HIV或AIDS。所有这些患者在诊断时都小于50岁。29例免疫功能低下患者中有5例（17%）在带状疱疹后发生急性视网膜坏死。在非免疫功能低下的带状疱疹患者中没有发现急性视网膜坏死。我们建议所有年龄小于50岁，初次检查时患有带状疱疹的患者进行HIV检测。此外，HIV感染患者在带状疱疹后应密切监测急性视网膜坏死的发展。长期口服预防以及初始大剂量静脉注射阿昔洛韦可能是适当的艾滋病毒感染者带状疱疹。
We conducted a review to investigate the prevalence of human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome (AIDS), in patients with herpes zoster ophthalmicus, as well as the incidence of acute retinal necrosis after herpes zoster ophthalmicus. All charts of patients seen at our institution between 1987 and 1992 with a primary diagnosis of herpes zoster ophthalmicus were reviewed. Of 112 patients with herpes zoster ophthalmicus, 29 (26%) had HIV or AIDS. All these patients were younger than 50 years at the time of diagnosis. Five of 29 (17%) immunocompromised patients had acute retinal necrosis after herpes zoster ophthalmicus. No acute retinal necrosis was identified in the nonimmunocompromised patients after herpes zoster ophthalmicus. We recommend that all patients younger than 50 years who have herpes zoster ophthalmicus at initial examination be tested for HIV. Additionally, HIV-infected patients should be monitored closely after herpes zoster ophthalmicus for development of acute retinal necrosis. Long-term oral prophylactic as well as initial high-dose intravenous acyclovir may be appropriate in HIV-infected individuals with herpes zoster.