Useful Field of View as a Reliable Screening Measure of Driving Performance in People With Parkinson's Disease: Results of a Pilot Study
Useful Field of View as a Reliable Screening Measure of Driving Performance in People With Parkinson's Disease: Results of a Pilot Study
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DOI：
10.1080/15389580903179901
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发表时间：
2009-01-01
影响因子：
2
通讯作者：
Fernandez, H. H.
中科院分区：
文献类型：
--
作者：
Classen, S.;McCarthy, D. P.;Fernandez, H. H.
目的：确定有用视野（UFOV）与帕金森病（PD）、视力和认知的其他临床测试与道路驾驶评估指标的相关性，并量化UFOV指示PD患者通过/未通过道路测试的能力。研究方法：随机选择19名特发性PD患者，平均年龄= 74.8（6.1）岁，14名（73.7%）男性，18名（94.7%）白人，与104名无PD的对照组年龄匹配。对照组的平均年龄为75.4岁（6.4岁），男性59名（56.7%），白人96名（92.3%）。在机构审查委员会批准后，这两组都被转介进行驾驶评估。结果如下：与视觉和认知的神经心理学和临床测试相比，UFOV显示出与标准化道路测试失败和驾驶错误数量的最强相关性（r. 75，p 0. 05）。在PD患者中，UFOV风险指数评分为3（范围1-5）被确定为通过道路测试的最佳截止值，灵敏度为87%，特异性为82%，AUC = 92%（SE 0.61，p = 0.002）。同样，UFOV 2（分散注意力）的最佳截止值为223 ms（范围16-500 ms），灵敏度为87.5%，特异性为81.8%，AUC = 91%（SE 0.73，p = 0.003）。UFOV 3（选择注意力）的最佳截止值为273 ms（范围16-500 ms），灵敏度为75%，特异性为72.7%，AUC = 87%（SE 0.81，p = 0.007）。结论：在PD患者中进行的这项初步研究中，UFOV可能是预测道路驾驶性能的上级筛选指标（与其他疾病、认知和视力指标相比），但其准确性必须在更大的PD患者样本中进行验证。
Purpose: To determine the correlations of the Useful Field of View (UFOV), compared to other clinical tests of Parkinson's disease (PD); vision; and cognition with measures of on-road driving assessments and to quantify the UFOV's ability to indicate passing/failing an on-road test in people with PD. Methods: Nineteen randomly selected people with idiopathic PD, mean age = 74.8 (6.1), 14 (73.7%) men, 18 (94.7%) Caucasians, were age-matched to 104 controls without PD. The controls had a mean age of 75.4 (6.4), 59 (56.7%) men, 96 (92.3%) Caucasians. Both groups were referred for a driving evaluation after institutional review board approval. Results: Compared to neuropsychological and clinical tests of vision and cognition, the UFOV showed the strongest correlations (r .75, p 0.05) with measures of failing a standardized road test and number of driving errors. Among PD patients, the UFOV Risk Index score of 3 (range 1-5) was established as the optimal cutoff value for passing the on-road test, with sensitivity 87 percent and specificity 82 percent, AUC = 92 percent (SE 0.61, p = .002). Similarly, the UFOV 2 (divided attention) optimum cutoff value is 223 ms (range 16-500 ms), sensitivity 87.5 percent, specificity 81.8 percent, AUC = 91 percent (SE 0.73, p = .003). The UFOV 3 (selected attention) optimal cutoff value is 273 ms (range 16-500 ms), sensitivity 75 percent, specificity 72.7 percent, AUC = 87 percent (SE 0.81, p = .007). Conclusion: In this pilot study among PD patients, the UFOV may be a superior screening measure (compared to other measures of disease, cognition, and vision) for predicting on-road driving performance but its rigor must be verified in a larger sample of people with PD.