Correlations between serum amyloid A protein and C-reactive protein in infectious diseases

Correlations between serum amyloid A protein and C-reactive protein in infectious diseases
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DOI:
10.1080/00365510310001636
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发表时间:
2003-01-01
影响因子:
2.1
通讯作者:
Friman, G
Friman, G
中科院分区:
医学4区
文献类型:
--
作者:
Lannergård, A;Larsson, A;Friman, G

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血清淀粉样蛋白A(SAA)是一种急性期反应物,近年来作为疾病和治疗监测的标志物越来越受到关注。我们将98例因病毒和细菌感染而入住传染病诊所的患者血清中SAA水平与C反应蛋白(CRP)水平相关联,这些病毒和细菌感染包括甲型肝炎和B型肝炎、巨细胞病毒感染、水痘带状疱疹、传染性单核细胞增多症、甲型流感、细菌性肺炎、链球菌性咽炎、细菌性脓毒症和严重细菌性脓毒症。从临床环境中选择研究人群作为这些常见患者组的代表。SAA水平与CRP水平显著相关(r(2)= 0.757,p
Serum amyloid A (SAA) protein is an acute phase reactant that has recently become of increasing interest as a marker for disease and treatment monitoring, We have correlated SAA levels to those of C-reactive protein (CRP) in sera from 98 patients admitted to an infectious diseases clinic because of viral and bacterial infections, including hepatitis A and B, cytomegalovirus infection, varicellae-zoster, infectious mononucleosis, influenza A, bacterial pneumonia, streptococcal pharyngitis, bacterial sepsis and severe bacterial sepsis. The study population was chosen from the clinical setting as representatives of these frequently encountered patient groups. SAA levels correlated significantly with CRP levels (r(2) = 0.757, p