Epilepsy and mortality in Africa: A review of the literature

Epilepsy and mortality in Africa: A review of the literature
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DOI:
10.1111/j.1528-1167.2005.00405.x
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发表时间:
2005-01-01
期刊:
影响因子:
5.6
通讯作者:
Hauser, WA
Hauser, WA
中科院分区:
医学1区
文献类型:
--
作者:
Diop, AG;Hesdorffer, DC;Hauser, WA

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问题:在非洲的许多地区,癫痫的患病率很高。这种情况受到歧视,诊断和治疗的保健人员和设施有限。人们怀疑癫痫存在巨大的治疗差距,数据显示,近80-85%的癫痫患者从未得到诊断或治疗。据世界范围内的报道,癫痫患者的死亡率比普通人群高出2 - 3倍。在非洲至少有这种幅度的增长,但数据很少。口头尸检的研究可能是一种方式进行研究的死亡率癫痫在Africa,因为这些方法不依赖于尸检,这是罕见的,或死亡证明,这是一个贫穷的来源,石油的信息在Africa.Methods:本文介绍了文献的死亡率癫痫发作后,在非洲,虽然有几个研究的死亡率之间的人与癫痫在Africa.Results:现有的研究表明,死亡的风险增加,癫痫相关的死亡比例更大。一项研究报告说,癫痫患者的死亡率增加了六倍。这是高于两到三倍的增长报告在发达countries.Conclusions:考虑到这种情况的高患病率,癫痫死亡率的公共卫生影响可能是巨大的。
Problem: The prevalence of epilepsy is high in many areas of Africa. This condition is stigmatized, and there are limited health personnel and facilities for diagnosis and treatment. A huge treatment gap is suspected for epilepsy, and data suggest that nearly 80-85% of people with epilepsy have never been diagnosed or treated. It is reported worldwide that the inmortality among people with epilepsy is two- to threefold higher than in general Population. An increase of at least this magnitude is suspected in Africa, but there are very few data. Verbal autopsy studies may be one way of carrying out studies of mortality for epilepsy in Africa because these methods do not rely on autopsies, which are rare, or upon death certificates, which are a poor source of information oil death in Africa.Methods: This paper presents the literature on mortality after seizures in Africa, although there are few studies of mortality among people with epilepsy in Africa.Results: The existing Studies Suggest an increased risk of dying and a greater proportion of deaths that are epilepsy-related. One Study reports a sixfold increase in mortality in people with epilepsy. This is higher than the two- to threefold increase reported in developed countries.Conclusions: Considering the high prevalence of this condition, the public health impact of epilepsy mortality is likely to be enormous.