Critical factors in assessing exposure to PBDEs via house dust

Critical factors in assessing exposure to PBDEs via house dust
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DOI:
10.1016/j.envint.2008.03.006
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发表时间:
2008-11-01
影响因子:
11.8
通讯作者:
Webster, Thomas F.
Webster, Thomas F.
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Allen, Joseph G.;McClean, Michael D.;Webster, Thomas F.

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评估多溴联苯醚的室内暴露需要对可能影响暴露估计和研究之间比较的方法进行严格审查。我们测量了从马萨诸塞州波士顿的20个家庭收集的住宅灰尘中的多溴联苯醚,以研究5个关键问题:1)灰尘暴露指标的选择,浓度(纳克/克)或粉尘载量(纳克/立方米(2))-影响分析和结果?2)粉尘浓度随时间变化的程度如何?3)不同房间的粉尘浓度是否不同?4)家用真空袋是研究人员收集的灰尘的可接受替代品吗?5)同一房间的空气和灰尘浓度是否相关?我们使用线性混合效应模型来分析数据,同时考虑家庭内和房间内的相关性。结果表明,PBDE粉尘浓度与地表负荷呈高度正相关(r=0.86-0.95,p
Assessment of indoor exposure to polybrominated diphenyl ethers (PBDEs) requires a critical examination of methods that may influence exposure estimates and comparisons between studies. We measured PBDEs in residential dust collected from 20 homes in Boston, MA, to examine 5 key questions: 1) Does the choice of dust exposure metric-e.g., concentration (ng/g) or dust loading (ng/m(2))-affect analysis and results? 2) To what degree do dust concentrations change over time? 3) Do dust concentrations vary between rooms? 4) Is the home vacuum bag an acceptable surrogate for researcher-collected dust? 5) Are air and dust concentrations correlated for the same room? We used linear mixed-effects models to analyze the data while accounting for within-home and within-room correlations. We found that PBDE dust concentration and surface loading were highly correlated (r=0.86-0.95, p