VODKA2: a fast and accurate method to detect non-standard viral genomes from large RNA-seq data sets.
VODKA2: a fast and accurate method to detect non-standard viral genomes from large RNA-seq data sets.
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DOI:
10.1261/rna.079747.123
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发表时间:
2023-12-18
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During viral replication, viruses carrying an RNA genome produce non-standard viral genomes (nsVGs), including copy-back viral genomes (cbVGs) and deletion viral genomes (delVGs), that play a crucial role in regulating viral replication and pathogenesis. Because of their critical roles in determining the outcome of RNA virus infections, the study of nsVGs has flourished in recent years, exposing a need for bioinformatic tools that can accurately identify them within next-generation sequencing data obtained from infected samples. Here, we present our data analysis pipeline, Viral Opensource DVG Key Algorithm 2 (VODKA2), that is optimized to run on a parallel computing environment for fast and accurate detection of nsVGs from large data sets.
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DOI:
10.1261/rna.077529.120
发表时间:
2020-12
期刊:
RNA (New York, N.Y.)
影响因子:
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作者:
Boussier J;Munier S;Achouri E;Meyer B;Crescenzo-Chaigne B;Behillil S;Enouf V;Vignuzzi M;van der Werf S;Naffakh N
通讯作者:
Naffakh N
影响因子:
6.7
作者:
Sun, Yan;Kim, Eun Ji;Lopez, Carolina B.
通讯作者:
Lopez, Carolina B.
影响因子:
5.4
作者:
Timm, Collin;Akpinar, Fulya;Yin, John
通讯作者:
Yin, John
影响因子:
14.9
作者:
Routh A;Johnson JE
通讯作者:
Johnson JE
DOI:
10.1261/rna.066910.118
发表时间:
2018-10
期刊:
RNA (New York, N.Y.)
影响因子:
--
作者:
Beauclair G;Mura M;Combredet C;Tangy F;Jouvenet N;Komarova AV
通讯作者:
Komarova AV