Surgical treatment of small bowel cancer: A 20-year single institution experience
Surgical treatment of small bowel cancer: A 20-year single institution experience
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DOI：
10.1016/j.gassur.2003.07.003
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发表时间：
2003-11-01
影响因子：
3.2
通讯作者：
Whang, EE
中科院分区：
文献类型：
--
作者：
Ito, H;Perez, A;Whang, EE
小肠恶性肿瘤很少见。本研究的目的是评估与小肠癌手术治疗相关的结果，并确定预后因素。回顾了在我院治疗超过20年的96例原发性小肠癌（不包括淋巴瘤）患者的病历。生存分析使用Kaplan-Meier方法（平均随访期5 - 7个月）。患者平均年龄为56岁，58%的患者为男性。60%的患者患有腺癌，21%患有肉瘤，19%患有类癌肿瘤。腺癌、肉瘤和类癌患者接受完全（治愈性）切除的百分比分别为51%、90%和50%。对于接受根治性切除术的腺癌患者，肿瘤（T）和淋巴结（N）分期是预测总生存率的重要预后因素。对于接受根治性切除的肉瘤患者，肿瘤分级是预测总生存率的重要预后因素。小肠类癌患者的预后是一致有利的。肉瘤和腺癌患者的预后通常较差，尽管具有良好预后因素的患者可以实现长期生存。(C)2003年消化道外科学会。
Small bowel malignancies are rare. The aims of this study were to evaluate the outcomes associated with surgical therapy for small bowel cancers and to define prognostic factors. The medical records of 96 consecutive patients with primary small bowel cancer (excluding lymphoma) treated at our institution over a 20 year period were reviewed. Survival was analyzed using the Kaplan-Meier method (mean follow-up period 5 7 months). Mean patient age was 56 years, and 58% of patients were male. Sixty percent of patients had an adenocarcinoma, 21% had a sarcoma, and 19% had a carcinoid tumor. The percentages of patients who underwent complete (curative) resection were 51%, 90%, and 50% for those with adenocarcinoma, sarcoma, and carcinoid tumor, respectively. For patients with adenocarcinoma who underwent curative resection, tumor (T) and node (N) stages were significant prognostic factors predicting overall survival. For patients with sarcomas who underwent curative resection, tumor grade was a significant prognostic factor predicting overall survival. The prognosis for patients with small intestinal carcinoid tumors is uniformly favorable. The prognosis for patients with sarcomas and adenocarcinomas is generally poor, although long-term survival is achieved by patients with favorable prognostic factors. (C) 2003 The Society for Surgery of the Alimentary Tract.