Hyperpolarized noble gas MR imaging of the lung: Potential clinical applications
Hyperpolarized noble gas MR imaging of the lung: Potential clinical applications
复制标题
DOI：
10.1016/s0720-048x(01)00347-3
复制
发表时间：
2001-10-01
影响因子：
3.3
通讯作者：
de Lange, EE
中科院分区：
文献类型：
--
作者：
Salerno, M;Altes, TA;de Lange, EE
超极化惰性气体是一类新型的磁共振造影剂。自从首次报道了肺部的超极化气体MR图像以来，人们对使用超极化气体来获得肺部空气空间的高空间和时间分辨率图像产生了相当大的兴趣。除了肺通气的静态图像之外，正在开发使用超极化气体来获得肺的动态、扩散和氧浓度图像的新技术。在这篇文章中，我们回顾了肺部超极化气体MRI的潜在临床应用，并讨论了各种肺部疾病的初步研究结果。超极化气体磁共振成像有潜力提供一个全面的形态和功能评估的肺。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
Hyperpolarized noble gases are a new class of MR contrast agent. Since the first hyperpolarized gas MR images of the lung were reported, there has been considerable interest in using hyperpolarized gas to obtain high spatial and temporal resolution images of the air spaces of the lung. In addition to static images of lung ventilation, new techniques are being developed using hyperpolarized gas to obtain dynamic, diffusion and oxygen concentration images of the lung. In this article, we review the potential clinical applications of pulmonary hyperpolarized gas MRI and discuss the preliminary findings in a variety of lung diseases. Hyperpolarized gas MRI has the potential to provide a comprehensive morphologic and functional assessment of the lung. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.