Micromachined piconewton force sensor for biophysics investigations
Micromachined piconewton force sensor for biophysics investigations
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DOI：
10.1063/1.2364118
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发表时间：
2006-10-23
影响因子：
4
通讯作者：
de Boer, Maarten P.
中科院分区：
文献类型：
--
作者：
Koch, Steven J.;Thayer, Gayle E.;de Boer, Maarten P.
作者描述了一种微机械力传感器，能够测量空气和水中小至 1 pN 的力。首先，他们测量了电磁体在粘在传感器上的单个 2.8 μm 磁珠上产生的力场。通过对 11 种不同的磁珠进行重复实验，他们测得饱和磁化强度的标准偏差为 9%。接下来，他们证明了传感器在浸入生理缓冲液中时可以完全发挥作用。这些结果表明，力传感器可用于磁力校准以及芯片上生物物理力的测量。 (c) 2006 年美国物理研究所。
The authors describe a micromachined force sensor that is able to measure forces as small as 1 pN in both air and water. First, they measured the force field produced by an electromagnet on individual 2.8 mu m magnetic beads glued to the sensor. By repeating with 11 different beads, they measured a 9% standard deviation in saturation magnetization. They next demonstrated that the sensor was fully functional when immersed in physiological buffer. These results show that the force sensors can be useful for magnetic force calibration and also for measurement of biophysical forces on chip. (c) 2006 American Institute of Physics.