CARBON-MONOXIDE IN BREATH IN RELATION TO SMOKING AND CARBOXYHEMOGLOBIN LEVELS

CARBON-MONOXIDE IN BREATH IN RELATION TO SMOKING AND CARBOXYHEMOGLOBIN LEVELS
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DOI:
10.1136/thx.36.5.366
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发表时间:
1981-01-01
期刊:
影响因子:
10
通讯作者:
BAILEY, A
BAILEY, A
中科院分区:
医学1区
文献类型:
--
作者:
WALD, NJ;IDLE, M;BAILEY, A

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对11,249名男性的CoHb水平进行了研究。在吸烟的2613名男性中的分布与在6641名不吸烟者(包括前吸烟者)中的分布完全分开。2005年雪茄和烟斗吸烟者的分布处于中等水平,尽管一些最高的COHb水平出现在雪茄吸烟者中。使用2%的COHb截止水平,81%的吸烟者、35%的雪茄和烟斗吸烟者以及1.0%的不吸烟者的COHb水平上升。用一种简单的呼吸采样技术采集了162名吸烟者和25名不吸烟者的肺泡空气样本。肺泡呼气中CO浓度与COHb水平高度相关(r=0.97),表明通过测量呼气中CO浓度可以可靠地估计COHb水平。肺泡CO测量是一种简单的方法来估计一个人是否可能是吸烟者。
CoHb levels were studied in 11,249 men. The distribution among the 2613 men who smoked cigarettes was well separated from that in 6641 non-smokers (including ex-smokers). The distribution for 2005 cigar and pipe smokers was intermediate, though some of the highest COHb levels occurred in cigar smokers. Using a COHb cut-off level of 2%, 81% of cigarette smokers, 35% of cigar and pipe smokers and 1.0% of non-smokers had raised COHb levels. Alveolar air samples were collected from 162 smokers and 25 non-smokers using a simple breath sampling technique. CO concentrations in alveolar breath were highly correlated with COHb levels (r = 0.97) indicating that COHb levels can be estimated reliably by measuring the concentration of CO in breath. Alveolar CO measurement was a simple method of estimating whether a person was likely to be a smoker.