l‐Lactate oxidase‐mediated removal of l‐lactic acid derived from fermentation medium for the production of optically pure D‐lactic acid
l‐Lactate oxidase‐mediated removal of l‐lactic acid derived from fermentation medium for the production of optically pure D‐lactic acid
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DOI：
10.1002/biot.202100331
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发表时间：
2022-01
影响因子：
4.7
通讯作者：
K. Okano;Yu Sato;Shnji Hama;Tsutomu Tanaka;H. Noda;A. Kondo;K. Honda
中科院分区：
文献类型：
--
作者：
K. Okano;Yu Sato;Shnji Hama;Tsutomu Tanaka;H. Noda;A. Kondo;K. Honda
对于生产立构复合体型聚乳酸而言，对光学纯的d -乳酸和l -乳酸的需求日益增加。由于木质纤维素生物质在自然界中大量存在，从木质纤维素生物质生产d -乳酸非常重要。玉米浆（CSL）是一种用于工业发酵的廉价氮源，尽管它含有大量的l -乳酸，这会降低所生产的d -乳酸的光学纯度。
There has been an increasing demand for optically pure d‐lactic and l‐lactic acid for the production of stereocomplex‐type polylactic acid. The d‐lactic acid production from lignocellulosic biomass is important owing to its great abundance in nature. Corn steep liquor (CSL) is a cheap nitrogen source used for industrial fermentation, though it contains a significant amount of l‐lactic acid, which decreases the optical purity of d‐lactic acid produced.