OVARIAN FUNCTION IN PIGS FOLLOWING HYPOPHYSIAL STALK TRANSECTION OR HYPOPHYSECTOMY
OVARIAN FUNCTION IN PIGS FOLLOWING HYPOPHYSIAL STALK TRANSECTION OR HYPOPHYSECTOMY
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DOI：
10.1152/ajplegacy.1967.212.5.1188
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发表时间：
1967-01-01
影响因子：
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通讯作者：
MELAMPY, RM
中科院分区：
文献类型：
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作者：
ANDERSON, LL;DYCK, GW;MELAMPY, RM
在发情或交配后的第二天，猪垂体柄横断后，黄体发育。到第12天，未交配的茎段切片动物中的细胞比交配的茎段切片动物中的细胞小，并且比第13天未交配或交配的对照猪中的细胞小。在第16天黄体孕酮浓度低于未交配比交配茎切片动物。到第20天，未交配和交配的茎切片猪的黄体退化。在第12天和第16天，在交配的茎切片动物的子宫中存在活胚胎，但在第20天仅发现坏死胚胎。Graafian卵泡在未交配和交配的茎切片猪中均退化。在具有持续黄体的垂体切除动物中，黄体退化在垂体柄横断后4天内开始，并在12天内完成。雌激素维持完整对照动物的黄体，但在发情或交配后的第二天，猪的茎切片中没有。干燥的猪垂体前叶或人绒毛膜促性腺激素维持猪子宫切除后垂体切除的黄体。
Corpora lutea developed in pigs following hypophysial stalk transection on the day after estrus or mating. By day 12 they were smaller in unmated stalk-sectioned animals than those in mated stalk-sectioned, as well as being smaller than those in day 13 unmated or mated control pigs. At day 16 luteal progesterone concentration was lower in unmated than mated stalk-sectioned animals. By day 20 corpora lutea regressed in unmated and mated stalk-sectioned pigs. Living embryos were present in the uteri of mated stalk-sectioned animals at days 12 and 16 but only necrotic embryos were found at day 20. Graafian follicles regressed in both unmated and mated stalk-sectioned pigs. In hysterectomized animals having persisting corpora lutea, luteal regression began within 4 days and was complete by 12 days after hypophysial stalk transection. Estrogen maintained corpora lutea in intact control animals but not in pigs stalk sectioned the day after estrus or mating. Desiccated porcine anterior pituitary or human chorionic gonadotrophin maintained corpora lutea in pigs hypophysectomized after hysterectomy.