The TRANSFAC system on gene expression regulation
The TRANSFAC system on gene expression regulation
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DOI：
10.1093/nar/29.1.281
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发表时间：
2001-01-01
影响因子：
14.9
通讯作者：
Urbach, S
中科院分区：
文献类型：
--
作者：
Wingender, E;Chen, X;Urbach, S
转录因子及其dna结合位点和谱的TRANSFAC数据库（http:// www.gene-regulation.de/）在数量上得到了扩展，并增加了一些模块。这些模块提供了调控区和转录因子基因（PathoDB）、支架/基质附着区（S/MARt DB）、信号转导（TRANSPATH）和基因表达源（CYTOMER）的病理相关突变信息。总之，这些不同的数据库模块构成了TRANSFAC系统。它们伴随着许多程序例程，用于识别潜在的转录因子结合位点或定位细胞调节网络中的单个组分。
The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http:// www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of modules. These modules give information about pathologically relevant mutations in regulatory regions and transcription factor genes (PathoDB), scaffold/matrix attached regions (S/MARt DB), signal transduction (TRANSPATH) and gene expression sources (CYTOMER). Altogether, these distinct database modules constitute the TRANSFAC system. They are accompanied by a number of program routines for identifying potential transcription factor binding sites or for localizing individual components in the regulatory network of a cell.