The unlimited potential of the great pond snail, Lymnaea stagnalis
The unlimited potential of the great pond snail, Lymnaea stagnalis
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DOI：
10.7554/elife.56962
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发表时间：
2020-06-16
期刊：
影响因子：
7.7
通讯作者：
Pirger, Zsolt
中科院分区：
文献类型：
--
作者：
Fodor, Istvan;Hussein, Ahmed A. A.;Pirger, Zsolt
只有少数动物物种适合成为多个生物学科的模式生物：其中之一是大池塘蜗牛，Stagnalis。自20世纪70年代以来被广泛用于研究神经生物学的基本机制，这种淡水蜗牛的价值也在宿主寄生虫相互作用，生态毒理学，进化，基因组编辑和“组学”以及人类疾病建模等领域得到了认可。虽然有关于这个物种的自然历史的知识，但目前缺乏的是实验室和实地调查结果的整合。基于此，本文旨在总结L。stagnalis，并指出，这种多用途模式生物是一个很好的，当代的选择，为解决大量不同的生物学问题，问题和现象。
Only a limited number of animal species lend themselves to becoming model organisms in multiple biological disciplines: one of these is the great pond snail, Lymnaea stagnalis. Extensively used since the 1970s to study fundamental mechanisms in neurobiology, the value of this freshwater snail has been also recognised in fields as diverse as host parasite interactions, ecotoxicology, evolution, genome editing and 'omics', and human disease modelling. While there is knowledge about the natural history of this species, what is currently lacking is an integration of findings from the laboratory and the field. With this in mind, this article aims to summarise the applicability of L. stagnalis and points out that this multipurpose model organism is an excellent, contemporary choice for addressing a large range of different biological questions, problems and phenomena.