Oncology of companion animals as a model for humans. an overview of tumor histotypes.
Oncology of companion animals as a model for humans. an overview of tumor histotypes.
复制标题
伴侣动物的肿瘤学作为人类的模型。
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
E. Spugnini
中科院分区：
文献类型：
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作者：
A. Porrello;P. Cardelli;E. Spugnini
The need for more appropriate animal models in cancer research has led, over the past 20 years, to consider pets with spontaneously occurring neoplasms as a valuable and still under used resource. The role of companion animals in the struggle to eradicate cancer can be multiple: they may act as environmental sentinels, help in gaining insights on tumor biology and finally may be enrolled in therapeutic trials which might act as a bridge to the clinic applications. This paper will focus on the most valuable spontaneous neoplasms in companion animals and will analyze the potentials of each histotype as a model for basic research and for new therapeutic strategies. It is conceivable that in the next years comparative oncology will play a paramount role in translational medicine allowing a rapid flow of data from laboratories to clinical application in humans.
