The effect of the canine popliteal node on the composition of lymph.

The effect of the canine popliteal node on the composition of lymph.
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犬腘淋巴结对淋巴成分的影响。

DOI:
10.1113/jphysiol.1983.sp014961
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发表时间:
1983
期刊:
The Journal of Physiology
影响因子:
--
通讯作者:
J. Pflug
J. Pflug
中科院分区:
--
文献类型:
--
作者:
P. Knox;J. Pflug

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比较了引流到犬窝淋巴结的传入淋巴和流出淋巴结的传出淋巴的成分。对其蛋白质组成和细胞组成进行了研究。25只灰狗的传出淋巴蛋白质浓度高于同侧肢体传出淋巴的蛋白质浓度。虽然狗之间蛋白质的绝对水平差异很大,但在特定的动物中,传入和传出淋巴的蛋白质含量之间的比例是恒定的。传出淋巴中的蛋白质浓度约为传出淋巴的两倍。淋巴的层析分析和放射性碘化犬血清白蛋白的使用表明,输出淋巴中蛋白质水平升高的原因是月国窝结将蛋白质集中在传入淋巴中。传出淋巴量在0.5×10(6)-4.3×10(6)个/ml之间,其中98%为淋巴细胞。不同犬的传出淋巴细胞密度与传入或传出蛋白质浓度之间无相关性,但当传入淋巴管内灌入不同蛋白质浓度的溶液时,传出液中的淋巴细胞数随灌流液中蛋白质浓度的增加而增加。根据其对液体平衡和免疫监测的意义,讨论了结节的聚集效应。
The composition of afferent lymph draining into the canine popliteal lymph node was compared with that of the efferent lymph leaving the node. Both the protein and cellular composition were studied. In twenty‐five greyhounds the protein concentration of efferent lymph was greater than that of afferent lymph collected from the same limb. Although the absolute level of protein varied greatly between dogs, in a particular animal there was a constant ratio between the protein content of afferent and efferent lymph. The concentration of protein in efferent lymph was approximately double that of afferent lymph. Chromatographic analysis of lymph and the use of radio‐iodinated canine albumin indicated that the reason for the increased level of protein in the efferent lymph is that the popliteal node concentrates the protein in afferent lymph. Afferent lymph contained less than 3 X 10(3) cells/ml; efferent lymph contained between 0.5 X 10(6) and 4.3 X 10(6) cells/ml, 98% of which were lymphocytes. In different dogs there was no correlation between efferent lymphocyte density and afferent or efferent protein concentration; however, when an afferent lymphatic was perfused with solutions of different protein concentration, the lymphocyte number in the efferent fluid became greater as protein concentration in the afferent perfusate was increased. The concentrating effect of the node is discussed in terms of its significance to both fluid balance and immunological surveillance.
静脉充血对热损伤狗爪子中液体和大分子的血液-淋巴运输的影响。
DOI: --
发表时间: 1981
期刊: Lymphology
影响因子: 2.5
作者:
Renkin,EM;Sloop,CS;Joyner,WL
通讯作者: Joyner,WL