The Arabidopsis genome.: An abundance of soluble N-ethylmaleimide-sensitive factor adaptor protein receptors
The Arabidopsis genome.: An abundance of soluble N-ethylmaleimide-sensitive factor adaptor protein receptors
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DOI：
10.1104/pp.124.4.1558
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发表时间：
2000-12-01
期刊：
影响因子：
7.4
通讯作者：
Raikhel, NV
中科院分区：
文献类型：
--
作者：
Sanderfoot, AA;Assaad, FF;Raikhel, NV
许多因子被认为是囊泡运输所必需的，包括许多通常被称为可溶性 N-乙基马来酰亚胺敏感因子接头蛋白受体 (SNARE) 成分的蛋白质。拟南芥基因组包含大量的 SNARE。一般来说，囊泡融合机制显得高度保守。然而，虽然拟南芥中似乎缺乏某些类型的酵母和哺乳动物基因，但这种小型植物基因组却具有其他真核生物中未发现的基因家族。人们对植物圈套的精确功能知之甚少。相比之下，大量植物 SNARE 的细胞内定位和相互作用已经确定，并且根据系统发育分析对这些数据进行了讨论。
Many factors have been characterized as essential for vesicle trafficking, including a number of proteins commonly referred to as soluble N-ethylmaleimide-sensitive factor adaptor protein receptor (SNARE) components. The Arabidopsis genome contains a remarkable number of SNAREs. In general, the vesicle fusion machinery appears highly conserved. However, whereas some classes of yeast and mammalian genes appear to be lacking in Arabidopsis, this small plant genome has gene families not found in other eukaryotes. Very little is known about the precise function of plant SNAREs. By contrast, the intracellular localization of and interactions between a large number of plant SNAREs have been determined, and these data are discussed in light of the phylogenetic analysis.