Analytical applications of MIPs in diagnostic assays: future perspectives.
Analytical applications of MIPs in diagnostic assays: future perspectives.
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DOI：
10.1007/s00216-015-9137-9
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发表时间：
2016-03
影响因子：
4.3
通讯作者：
Whitcombe MJ
中科院分区：
文献类型：
--
作者：
Bedwell TS;Whitcombe MJ
已经做出许多努力来生产具有仿生性质的人工材料以用于结合测定。在这些努力中，分子印迹技术由于对感兴趣的分子可获得的高选择性、所产生的聚合物的稳健性、简单和短的合成以及优异的成本效率而受到广泛关注。在这篇综述中，分子印迹吸附剂分析领域的进展进行了讨论，重点是从2005年至今的工作。近年来，分子印迹聚合物在各种检测形式中作为抗体的替代品的使用呈增长趋势，该领域的出版物稳步增加（见图）。
Many efforts have been made to produce artificial materials with biomimetic properties for applications in binding assays. Among these efforts, the technique of molecular imprinting has received much attention because of the high selectivity obtainable for molecules of interest, robustness of the produced polymers, simple and short synthesis, and excellent cost efficiency. In this review, progress in the field of molecularly imprinted sorbent assays is discussed—with a focus on work conducted from 2005 to date. A growing trend in recent years has been the use of molecularly imprinted polymers as replacements for antibodies in various assay formats, as indicated by a steady increase in publications in the area (see graph)