Synthesis of vitamins by intestinal bacteria
Synthesis of vitamins by intestinal bacteria
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DOI：
10.1073/pnas.28.7.285
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发表时间：
1942-01-01
影响因子：
11.1
通讯作者：
McVeigh, I
中科院分区：
文献类型：
--
作者：
Burkholder, PR;McVeigh, I
生物素、核黄素、烟酸和硫胺素的产量各不相同。用大肠杆菌、普通变形杆菌、产气杆菌、产碱杆菌、肠系膜芽孢杆菌和普通芽孢杆菌的纯培养物，除普通变形杆菌不能产生烟酸和B外，其余菌株均不能产生烟酸和B。肠系膜不能产生可检测量的生物素。产生的生物素总是比其他维生素少得多。显然，这些细菌合成的B族维生素超过了它们的需要量。111小时后，滤液含有30-40%的由Bact产生的4种维生素。产气菌
Biotin, riboflavin, nicotinic acid and thiamine are produced in varying amts. by pure cultures of Escherichia coli, Proteus vulgaris, Bac-terium aerogenes, Alkaligenes jecalis, Bacillus mesentericus and Bacillus vulgatus except that P. vulgaris fails to produce nicotinic acid and B. mesentericus fails to produce biotin in detectable quantities. Far less biotin is always produced than of the other vitamins. Evidently these bacteria synthesize B vitamins in excess of their requirements. After 111 hr. the filtrate contains 30-40% of the 4 vitamins produced by Bact. aerogenes.