Therapeutic effect of forest bathing on human hypertension in the elderly
Therapeutic effect of forest bathing on human hypertension in the elderly
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DOI：
10.1016/j.jjcc.2012.08.003
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发表时间：
2012-11-01
影响因子：
2.5
通讯作者：
Yan, Jing
中科院分区：
文献类型：
--
作者：
Mao, Gen-Xiang;Cao, Yong-Bao;Yan, Jing
目的：为森林浴作为人类高血压自然疗法的疗效提供科学证据。方法：将24名老年原发性高血压患者随机分为两组，每组12人。一组被送往常绿阔叶林体验7天7夜的旅行，另一组被送往杭州市区进行对照。检测血压指标，内皮素1、同型半胱氨酸、肾素、血管紧张素原、血管紧张素II、血管紧张素II 1型受体、血管紧张素II 2型受体等心血管疾病相关病理因子以及炎症细胞因子白介素6、肿瘤坏死因子α。同时，使用情绪状态轮廓（POMS）评估来评估受试者情绪状态的变化。此外，在7天内同时监测两个实验点的空气质量。结果：受试者各项指标基线无显着差异。实验结束后，城市组检测指标变化不大。与城市人群相比，暴露在森林环境中的受试者的血压显着降低。暴露于森林环境的受试者的生物指标值也低于城市对照组和自身的基线水平。 POMS评估显示，暴露于森林环境后，负分量表的得分降低。除了。负离子、PM 10（颗粒物）定量检测显示，森林环境空气质量明显优于市区。
Objective: To provide scientific evidence supporting the efficacy of forest bathing as a natural therapy for human hypertension.Methods: Twenty-four elderly patients with essential hypertension were randomly divided into two groups of 12. One group was sent to a broad-leaved evergreen forest to experience a 7-day/7-night trip, and the other was sent to a city area in Hangzhou for control. Blood pressure indicators, cardiovascular disease-related pathological factors including endothelin-1, homocysteine, renin, angiotensinogen, angiotensin II, angiotensin II type 1 receptor, angiotensin II type 2 receptor as well as inflammatory cytokines interleukin-6 and tumor necrosis factor alpha were detected. Meanwhile, profile of mood states (POMS) evaluation was used to assess the change of mood state of subjects. In addition, the air quality in the two experimental sites was monitored during the 7-day duration, simultaneously.Results: The baselines of the indicators of the subjects were not significantly different. Little alteration in the detected indicators in the city group was observed after the experiment. While subjects exposed to the forest environment showed a significant reduction in blood pressure in comparison to that of the city group. The values for the bio-indicators in subjects exposed to the forest environment were also lower than those in the urban control group and the baseline levels of themselves. POMS evaluation showed that the scores in the negative subscales were lowered after exposure to the forest environment. Besides. the air quality in the forest environment was much better than that of the urban area evidenced by the quantitative detection of negative ions and PM 10 (particulate matter