MEASUREMENT OF TRANSLATIONAL DISPLACEMENT PROBABILITIES BY NMR - AN INDICATOR OF COMPARTMENTATION
MEASUREMENT OF TRANSLATIONAL DISPLACEMENT PROBABILITIES BY NMR - AN INDICATOR OF COMPARTMENTATION
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DOI：
10.1002/mrm.1910140303
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发表时间：
1990-06-01
影响因子：
3.3
通讯作者：
GARROWAY, AN
中科院分区：
文献类型：
--
作者：
CORY, DG;GARROWAY, AN
本文介绍并论证了核磁共振脉冲梯度受激回波法直接获得液体分子平移位移几率（位移剖面）的方法。位移分布的时间发展反映了扩散的存在、对扩散的限制（例如，壁、膜）、流动和空间依赖性弛豫汇。这种方法允许研究太小而不能通过常规NMR成像方法观察到的隔室。隔室空间特性的分布可以在约0.1至25 μm的空间范围内表征，完全独立于各个隔室的绝对空间位置。出版社：Academic Press，Inc.
We introduce and demonstrate an NMR pulsed gradient stimulated echo method of directly obtaining the molecular translational displacement probability (displacement profile) of a liquid. The temporal development of the displacement profile reflects the presence of diffusion, restrictions to diffusion (e.g., walls, membranes), flow, and spatially dependent relaxation sinks. This approach allows the study of compartments which are too small to be observed by conventional NMR imaging methods. The distribution of spatial properties of compartments can be characterized over a spatial field of about 0.1 to 25 μm, completely independent of the absolute spatial location of the individual compartments. © 1990 Academic Press, Inc.