Nanomaterials in Animal Husbandry: Research and Prospects.
Nanomaterials in Animal Husbandry: Research and Prospects.
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纳米材料在畜牧业中的应用：研究与展望
DOI：
10.3389/fgene.2022.915911
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发表时间：
2022
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
抗炎、抗病毒和抗癌治疗是纳米材料在生物学中的潜在应用。为了探索纳米技术的最新发现，我们回顾了已发表的文献，重点是用于抗炎和抗肿瘤特性的共组装纳米颗粒及其在畜牧业中的应用。结果表明，纳米粒具有显著的抗炎和抗肿瘤作用，在动物育种中具有广阔的应用前景。此外，汇总的证据表明，该机制是通过间接或直接靶向疾病部位的特定药物负载对炎症和肿瘤产生积极影响。由于精确的调控机制尚不清楚，大多数研究都集中在通过靶向功能性共组装纳米颗粒来调控细胞核中的特定位点甚至特定基因。因此，尽管纳米技术在养殖动物中的应用前景很吸引人，但大多数结果还不能转化为现场应用。总体而言，纳米材料在抗炎和抗肿瘤方面优于同类材料。纳米技术在畜牧业和兽医护理方面也有很好的应用前景，其在畜牧业中的应用和发展仍然是一个令人兴奋的研究领域。
Anti-inflammatory, antiviral, and anti-cancer treatments are potential applications of nanomaterials in biology. To explore the latest discoveries in nanotechnology, we reviewed the published literature, focusing on co-assembled nanoparticles for anti-inflammatory and anti-tumor properties, and their applications in animal husbandry. The results show that nanoparticles have significant anti-inflammation and anti-tumor effects, demonstrating broad application prospects in animal breeding. Furthermore, pooled evidence suggests that the mechanism is to have a positive impact on inflammation and tumors through the specific drug loading by indirectly or directly targeting the disease sites. Because the precise regulatory mechanism remains unclear, most studies have focused on regulating particular sites or even specific genes in the nucleus by targeting functional co-assembled nanoparticles. Hence, despite the intriguing scenarios for nanotechnology in farmed animals, most results cannot yet be translated into field applications. Overall, nanomaterials outperformed similar materials in terms of anti-inflammatory and anti-tumor. Nanotechnology also has promising applications in animal husbandry and veterinary care, and its application and development in animal husbandry remain an exciting area of research.