Overview of Basic Mechanisms of Cardiac Arrhythmia.
Overview of Basic Mechanisms of Cardiac Arrhythmia.
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DOI：
10.1016/j.ccep.2010.10.012
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发表时间：
2011-03-01
影响因子：
--
通讯作者：
Burashnikov A
中科院分区：
文献类型：
--
作者：
Antzelevitch C;Burashnikov A
心律失常简单地定义为与正常心率和/或节律的变化，其在生理学上是不合理的。近年来，我们对各种心律失常发生的电生理机制的理解取得了重要进展。导致心律失常的机制通常分为两大类：（1）增强或异常冲动形成（即，局灶性活动）和（2）传导障碍（即，折返）（图1）。
A cardiac arrhythmia simply defined is a variation from the normal heart rate and/or rhythm that is not physiologically justified. Recent years have witnessed important advances in our understanding of the electrophysiologic mechanisms underlying the development of a variety of cardiac arrhythmias. The mechanisms responsible for cardiac arrhythmias are generally divided into 2 major categories:(1) enhanced or abnormal impulse formation (ie, focal activity) and (2) conduction disturbances (ie, reentry)(Fig. 1).