Volatile aldehydes in the mainstream smoke of the narghile waterpipe
Volatile aldehydes in the mainstream smoke of the narghile waterpipe
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DOI：
10.1016/j.fct.2008.09.007
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发表时间：
2008-11-01
影响因子：
4.3
通讯作者：
Saliba, N. A.
中科院分区：
文献类型：
--
作者：
Al Rashidi, M.;Shihadeh, A.;Saliba, N. A.
人们对纳吉尔烟产生的有毒物质的质量和数量知之甚少，随着这种吸烟方法在全世界流行起来，这一问题变得越来越重要。本研究关注的是识别和定量的挥发性醛在气体和颗粒阶段的主流纳格尔烟产生使用一种流行类型的调味马塞尔烟草混合物。这些化合物的分析是基于环境保护署汇编方法TO-11A的改进版本。采用标准化抽烟机方案，抽烟次数为171次，抽烟时间为2.6 s，抽烟间隔为17 s，甲醛、乙醛、丙烯醛、丙烯醛和甲基丙烯醛的平均产率分别为630、2520、892、403和106 μ g/次。结果表明，除甲醛外，本研究中鉴定的醛类均未在烟雾的颗粒相中发现，甲醛的分配系数估计为K-p = 3.3 x 10(-8) mu g/m(3)。鉴于先前报道的挥发性醛的肺吸收分数约为90%，本研究中测量的产量足以诱发各种疾病，这取决于吸烟者的接触程度和呼吸方式。(C) 2008 Elsevier Ltd版权所有。
Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma'ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6 s puff duration and 17 s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106 mu g/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as K-p = 3.3 x 10(-8) mu g/m(3). Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. (C) 2008 Elsevier Ltd. All rights reserved.