Algorithms for Computational Biology - Second International Conference, AlCoB 2015, Mexico City, Mexico, August 4-5, 2015, Proceedings

Algorithms for Computational Biology - Second International Conference, AlCoB 2015, Mexico City, Mexico, August 4-5, 2015, Proceedings
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计算生物学算法 - 第二届国际会议,AlCoB 2015,墨西哥墨西哥城,2015 年 8 月 4-5 日,会议记录

DOI:
10.1007/978-3-319-21233-3_3
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发表时间:
2015
期刊:
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通讯作者:
Ladroue C
Ladroue C
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文献类型:
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作者:
Ladroue C

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合成生物学旨在通过生物部件的标准化和遵循工程原理来促进新生物的设计。我们推出了 gc(遗传编译助手),这是一种软件工具,可以根据最少的要求自动构建 DNA 的功能序列。通过简单的语言,用户提供有关其构造的内部知识(例如部件的相对位置、限制性酶的数量)。atgcc 结合来自已建立的生物学、用户知识和生物信息学数据库的信息,并将问题映射到约束满足设置。该解决方案是准备组装并转移到目标生物体的功能性 DNA 序列。
Synthetic biology aims at facilitating the design of new organisms via the standardization of biological parts and following engineering principles. We presentatgc(Assistant To Genetic Compilation), a software tool that automatically builds a functional sequence of DNA from a minimal set of requirements. Through a simple language, the user provides in-house knowledge about their construct (e.g.relative placement of parts, number of restriction enzymes).atgccombines information from established biology, user knowledge and bioinformatics databases, and maps the problem to a constraint satisfaction setting. The solution is a functional DNA sequence ready to be assembled and transferred to a target organism.