Reintegrating Biology Through the Nexus of Energy, Information, and Matter
Reintegrating Biology Through the Nexus of Energy, Information, and Matter
复制标题
通过能量、信息和物质的联系重新整合生物学
DOI：
10.1093/icb/icab174
复制
发表时间：
2021
影响因子：
2.6
通讯作者：
Buan, Nicole R
中科院分区：
文献类型：
--
作者：
Hoke, Kim L;Zimmer, Sara L;Roddy, Adam B;Ondrechen, Mary Jo;Williamson, Craig E;Buan, Nicole R
信息、能量和物质是生物组织各个层次的基本属性，生命是从物质、能量和信息的持续流动中产生的。这篇透视文章定义并解释了这一关系的三大支柱。我们建议，物质，能量和信息之间的复杂的相互转换，包括这个关系的定量表征将有助于我们获得生物学的见解，连接现象在不同层次的生物组织。我们从多个生物尺度阐明的例子，强调这种联系的方法如何导致更完整的理解生物系统。能量、信息和物质的混合可以提供一种共同的货币，帮助将生物组织的各个层次的现象联系起来。能量和信息通过生物组织层次的传播可以导致影响其他层次的突发特性和系统范围的变化。更深入地考虑能量、信息和物质的测量不平衡可以帮助研究人员确定在一个尺度上影响系统功能的关键因素，突出了将生物组织各个层面的现象联系起来的途径，并开发了生物系统的预测模型。
Information, energy, and matter are fundamental properties of all levels of biological organization, and life emerges from the continuous flux of matter, energy, and information. This perspective piece defines and explains each of the three pillars of this nexus. We propose that a quantitative characterization of the complex interconversions between matter, energy, and information that comprise this nexus will help us derive biological insights that connect phenomena across different levels of biological organization. We articulate examples from multiple biological scales that highlight how this nexus approach leads to a more complete understanding of the biological system. Metrics of energy, information, and matter can provide a common currency that helps link phenomena across levels of biological organization. The propagation of energy and information through levels of biological organization can result in emergent properties and system-wide changes that impact other hierarchical levels. Deeper consideration of measured imbalances in energy, information, and matter can help researchers identify key factors that influence system function at one scale, highlighting avenues to link phenomena across levels of biological organization and develop predictive models of biological systems.