Pulmonary alveolar proteinosis associated with psoriasis and complicated by mycobacterial infection: Successful treatment with granulocyte-macrophage colony stimulating factor after a partial response to whole lung lavage
Pulmonary alveolar proteinosis associated with psoriasis and complicated by mycobacterial infection: Successful treatment with granulocyte-macrophage colony stimulating factor after a partial response to whole lung lavage
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DOI：
10.1111/j.1440-1843.2004.00594.x
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发表时间：
2004-08-01
期刊：
影响因子：
6.9
通讯作者：
Phillips, MJ
中科院分区：
文献类型：
--
作者：
Rahman, JAA;Moodley, YP;Phillips, MJ
肺泡蛋白沉积症是一种罕见的肺部疾病。虽然全肺灌洗被认为是最有效的治疗方法，但并非每个患者都表现出完全的反应。一名年轻男子PAP与银屑病谁经历了频繁的全肺灌洗，但只有达到缓解后，粒细胞-巨噬细胞集落刺激因子（GM-CSF）治疗的情况下报告。他的肺部问题并发非典型分枝杆菌感染，经治疗解决。并对GM-CSF的作用进行了讨论。
Pulmonary alveolar proteinosis (PAP) is a rare lung disease. Although whole lung lavage is considered the most effective treatment, not every patient shows a complete response. The case of a young man with PAP in association with psoriasis who underwent frequent whole lung lavage but only achieved remission following treatment with granulocyte-macrophage colony stimulating factor (GM-CSF) is reported. His lung problem was complicated by atypical mycobacterial infection, which resolved with treatment. The role of GM-CSF is discussed.