Lack of spontaneous activity of cutaneous spinal dorsal horn neurons in awake, drug-free, spinally transected cats.

Lack of spontaneous activity of cutaneous spinal dorsal horn neurons in awake, drug-free, spinally transected cats.
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清醒、未用药、脊髓横断的猫的皮肤脊髓背角神经元缺乏自发活动。

DOI:
10.1016/0014-4886(87)90048-3
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发表时间:
1987
影响因子:
5.3
通讯作者:
Tang,J
Tang,J
中科院分区:
医学2区
文献类型:
--
作者:
Collins,JG;Ren,K;Tang,J

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在脊髓横断(T12)之前(数周)和之后(第1天至第7天),记录清醒、无药物猫脊髓背角(L4-L 6)中具有皮肤输入的神经元的细胞外单单位活动。在两种记录条件下,神经元的自发活动都很小或不存在。脊髓横断后自发活动的缺乏与急性脊髓横断制备中记录的活动形成鲜明对比,在急性脊髓横断制备中报告了高自发活动率。这种差异可能反映了慢性、清醒、无药物和急性制剂之间的重要差异。
Extracellular single-unit activity was recorded from neurons with cutaneous input in the dorsal horn of the spinal cord (L4–L6) of awake, drug-free cats before (for several weeks) and after (day 1 through day 7) cord transection (T12). The spontaneous activity of the neurons was minimal or nonexistent in both recording conditions. The lack of spontaneous activity following spinal cord transection contrasts sharply with activity recorded in acute spinal-cord transected preparations in which high rates of spontaneous activity have been reported. This discrepancy may reflect an important difference between the chronic, awake, drug-free and acute preparations.
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